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DNA Romance
DNA Romance
报名

关系匹配背后的科学

DNA Romance predicts "chemistry" online using the DRom 1.0 algorithm. It assesses 100 specific markers within your DNA - focused on genes proven to be involved in attraction and reproduction. Studies have shown that people with varied DNA markers in the Major Histocompatibility Complex (MHC) tend to find each other's scent appealing and often enjoy more durable romantic relationships.

DRom 1.0 - Predicting Chemistry

DRom 1.0 algorithm - DNA Romance predicts chemistry from MHC markers

DNA浪漫也预测 性格相容性 using Myers-Briggs personality types, lets users evaluate shared common interests via filters, and 物理吸引力 based on photographs.

Our second algorithm, DRom 2.0, uses an AI model trained with relevant DNA markers to predict phenotypic traits with high accuracy - complementing the profile-verification mechanism that checks user authenticity.

性格相容性评分

不同人格类型如何在人际关系中相互作用

Our personality compatibility rating draws on the Jung / Myers-Briggs 16 personality types a psychometric framework with over a century of development. Carl Jung's 1921 work was refined by Isabel Briggs Myers and Katherine Briggs into the Myers-Briggs Type Indicator®, widely used today in organisational psychology.

DNA Romance applies this framework to predict potential connections between singles and couples - assigning higher compatibility scores to similar personality types, lower scores to those that tend to conflict.

DNA Romance personality compatibility - 16 Myers-Briggs personality types

重点研究论文

Selected peer-reviewed studies underpinning the science behind DNA Romance.

Dandine-Roulland 等, 2019

丹丁-鲁兰德C,劳伦特R,达拉拉I,图潘斯B和夏克斯R(2019年)

人类 MHC 不相配交配的基因组证据

英国皇家学会学报B

北欧的夫妇倾向于表现出MHC的差异,表明生物因素对配偶选择有影响。其他地方的文化和社会因素可能会掩盖生物驱动的模式。

Birnbaum et al., 2019

Birnbaum GE, Zholtack K, Mizrahi M & Ein-Dor T (2019)

苦药:停用口服避孕药增强了人们的吸引力另类伴侣

Evolutionary Psychological Science 5, 276–285

激素避孕药会改变配偶偏好。停止使用会使这些偏好恢复,并增强对基因相容男性的吸引力,尤其是在高生育阶段。

Wedekind, 2019

Wedekind C (2019)

气味愉悦度与强度之间的预测互动为女性的主要组织相容性复合体社交信号提供了证据

Proc. R. Soc. B 285:20172714

Re-analysis of MHC-and-odour data showing odour pleasantness and intensity interact with MHC dissimilarity to influence social signalling - a more nuanced relationship between MHC, scent perception, and communication than earlier studies suggested.

Henningsson et al., 2017

Henningsson S et al. (2017)

主要组织相容性复合体 (MHC) 和性伴侣选择

Translational Psychiatry 7:e1118

系统地研究人类的MHC和性选择,评估现代人群中HLA基因型和伴侣选择之间的关系。

Christakis & Fowler, 2014

Christakis NA, Fowler JH (2014)

友谊与自然选择

PNAS 111(suppl 3): 10796–10801

朋友分享的基因相似性与四代表亲相当。表明社会关系沿着微妙的生物梯度形成,不仅是共享的环境 - 与浪漫的相容性如何扩展到MHC之外有关。

Garver-Apgar et al., 2006

Garver-Apgar CE, Gangestad SW, Thornhill R, Miller RD, Olp JJ (2006)

主要组织相容性复合体等位基因、性反应性与浪漫伴侣中的不忠行为

Psychological Science 17:830-835

MHC相似性较高的夫妇报告说性反应降低,不忠率较高 - 已建立关系中MHC相容性的直接行为关联。

Roberts et al., 2006

Roberts SC, Gosling LM, Carter V, Petrie M (2006)

人类的MHC相关气味偏好与口服避孕药的使用

Proc. R. Soc. B 275:2715-2722

女性的MHC相关的气味偏好在使用激素避孕药时会发生逆转——她们会转向与MHC相似的伴侣,而不是与MHC不同的伴侣。

Wedekind & Furi, 1997

Wedekind C, Furi S (1997)

男性和女性对体味的偏好:他们的目标是特定的MHC组合还是普遍的杂合性?

Proc. R. Soc. B 264:1471-1479

Follow-up to the classic t-shirt study. Men and women evaluated odour samples from MHC-typed donors; preferences fell on MHC-dissimilar partners more often than chance - but the underlying signal favours heterozygosity rather than specific allele combinations.

Wu et al., 2018

Wu K, Chen C, Moyzis RK, Nuno M, Yu Z and Greenberger E (2018)

超越肤浅:基于主要组织相容性复合体(MHC)的亚裔美国人快速约会者之间的吸引力

Evolution and Human Behavior. 39(4):447-456.

在速配约会的背景下,女性(但不是男性)通过SNP分析表现出对伴侣的主要组织相容性(MHC)的偏好,不同的SNP根据与主要HLA基因的接近程度有不同的吸引力,MHC基索引与自我报告的人格特征在预测双方第二次约会的机会时具有可比的影响。

Burger等,2017年

Burger D, Meuwly C, Marti E, Sieme H, Oberthür M, Janda J, Meinecke-Tillmann S and Wedekind C (2017)

MHC-correlated preferences in diestrous female horses (Equus caballus)

Theriogenology. 89:318-323.

本研究调查了主要组织相容性复合体(MHC)基因和睾酮水平对雌马交配偏好的影响,发现母马在其黄体期(非生殖期)对MHC不相似的种马表现出更高的兴趣,但其他非MHC相关的雄性特征,可能如身体属性或行为线索,在其发情期(生殖期)可能会覆盖MHC的影响,背景和周期阶段在配偶选择中起着关键作用。

Sherlock et al., 2016

Sherlock JM, Sidari MJ, Harris EA, Barlow FK, Zietsch BP (2016)

Testing the mate-choice hypothesis of the female orgasm: disentangling traits and behaviours .

Socioaffect Neurosci Psychol. 6:31562.

研究表明,女性在与不同伴侣的性行为中会有不同的高潮频率,这些伴侣被认为更有幽默感、创造力、温暖、忠诚,并且更能体会伴侣的性满足感,这部分支持了女性高潮作为选择优质伴侣的机制的假设,即配偶选择假说。

Kromer et al., 2016

Kromer J, Hummel T, Pietrowski D, Giani AS, Sauter J, Ehninger G, Schmidt AH, Croy I (2016)

Influence of HLA on human partnership and sexual satisfaction .

Sci Rep. 6:32550.

研究表明,在人类中,HLA(免疫系统的一个遗传组件)的不相似性可能通过检测与遗传兼容性相关的嗅觉线索来影响配偶选择和性满足,类似于其他动物中观察到的机制,促进后代的遗传多样性和对病原体的抗性。

Wlodarski and Dunbar., 2015

Wlodarski R. and Dunbar RIM. (2015)

What’s in a Kiss? The Effect of Romantic Kissing on Mate Desirability .

Evol Psychol. ; 12(1): 178–199.

这项研究发现,被认为的浪漫接吻能力会影响对潜在伴侣的评价,尤其是在休闲性行为情境中,对女性的吸引力会更大,而在某些交配情景中,视觉线索可以抵消接吻相关信息的影响,但有吸引力的视觉信息对男性的影响似乎更为显著,这暗示了接吻在传达伴侣质量和吸引力方面与其他线索一起扮演多面向的角色。

Burger等,2015年

Burger D, Dolivo G, Marti E, Sieme H and Wedekind C (2015)

雌性大型主要组织相容性复合体类型会影响马(Equus caballus)的睾丸素水平和精子数量。

Proc. R. Soc. B 282:20150407

这项研究考察了主要组织相容性复合体(MHC)如何影响马的雄性生殖策略。研究发现,当雄马暴露在MHC类型不同的母马身上时,它们的睾丸激素水平会更高,每次射精的精子数量也会比暴露在MHC类型相似的母马身上的雄马更多,这表明MHC相关的信号确实可以影响雄性睾丸激素的产生和精液特性,从而影响生殖策略。

Laurent and Chaix., 2012

Lie et al., 2010

Lie HC, Simmons LH and Rhodes G (2010)

Genetic dissimilarity, genetic diversity, and mate preferences in humans .

Evolution and Human Behavior 31:8–58.

本研究探讨了遗传因素,特别是主要组织相容性复合体(MHC),对人类伴侣偏好的影响,发现男性在短期和长期交配环境中倾向于偏好MHC不相似的女性,而遗传多样性影响男性和女性在不同交配环境中的伴侣偏好,从而支持MHC在人类伴侣选择中的重要作用,并暗示这些偏好可能有助于增强后代的遗传多样性。

Lie et al., 2010b

Lie HC, Rhodes G and Simmons LH (2010)

Is genetic diversity associated with mating success in humans ?

Animal Behaviour. 79, 4:903-909

这项研究表明,在人类中,尤其是女性,遗传多样性,特别是在主要组织相容性复合体(MHC)内,与更高的交配成功率相关,这一成功率通过性伴侣的数量来衡量,支持了遗传因素可能与免疫系统功能相关的概念在人的交配成功中发挥作用,而在男性中未发现显著关联。

Chaix et al., 2008

Chaix R, Cao C, and Donnelly P (2008)

Is Mate Choice in Humans MHC-Dependent ?

PLOS Genetics, 4 (9)

研究表明,尽管欧洲裔美国人群可能更倾向于选择MHC不相似的伴侣,以促进后代免疫系统的多样性,但在所研究的非洲人群中并未发现这种模式,这表明MHC对伴侣选择的影响可能是依赖于情境的,并可能受到各种因素的影响。

Schwensow 等人,2008 年

Schwensow N, Fietz J, Dausmann K, Sommer S (2008)

MHC-associated mating strategies and the importance of overall genetic diversity in an obligate pair-living primate .

Evol Ecol. (22) 617-636

这项研究探讨了脂尾矮狐猴的配偶选择,发现雌性更倾向于选择具有更大MHC基因多样性和较低MHC重叠的雄性作为社会父亲和遗传父亲,而整体遗传杂合性和亲缘关系对配偶选择没有显著影响;额外配对交配可能发生以减轻遗传不兼容性,突显了“良好基因作为杂合性”和“异配交配”假说在灵长类动物交配策略中的复杂相互作用。

Wedekind., 2007

Wedekind C (2007)

The Major Histocompatibility Complex and Perfumers’ Descriptions of Human Body Odors

Evolutionary Psychology.5(2): 330-343

这个实验揭示了主要组织相容性复合体(MHC)与人类体味的语言描述之间的联系,表明专业香水师在某种程度上能够表达与MHC相关的体味成分,强调了MHC对人类嗅觉感知的影响,以及在选择伴侣时的潜在作用,因为MHC在免疫系统功能中扮演着关键角色,并且之前已经注意到它对体味和伴侣选择的影响。

Wedekind., 2006

Wedekind C (2006)

The Intensity of Human Body Odors and the MHC: Should We Expect A Link ?

Evolutionary Psychology. 4:85-94

这项研究辨别了几个MHC(主要组织相容性复合体)基因与男性体味的强度和愉悦感之间的关系,发现至少有一个纯合子MHC抗原的男性并不会释放出明显更强烈的气味,而异合子的气味却被具有不同MHC的女性感知为显著更强。

Pause et al., 2006

Pause BM, Krauel K, Schrader C, Sojka B, Westphal E, Mu¨ller-Ruchholtz W, and Ferstl R. (2006)

人脑是一个检测通过化学感知传递的HLA-I类相似性在同性和异性关系中的探测器。

Proc. R. Soc. B (2006) 273, 471–478 doi:10.1098/rspb.2005.3342

This study reveals that humans subconsciously detect and respond to body odors from individuals with similar HLA (Human Leucocyte Antigen) genetic markers, which might play a critical role in social interactions and mate selection by acting as subtle social signals within both same-sex and opposite-sex relationships..

Martins et al., 2005

Martins Y, Preti G, Crabtree CR, Runyan T, Vainius AA and Wysocki CJ (2005)

Preference for Human Body Odors Is Influenced by Gender and Sexual Orientation .

Psychological Science, 16(9) 694-702

这项研究表明,性取向和性别影响个体对人体气味的偏好,异性恋和同性恋的男性和女性在面对来自不同性别和性取向组合的个体的体味时,展示出明显的二选一偏好,这意味着体味可能是性伴侣和社交伴侣选择中的一个因素。

Horton et al., 2004

Horton R, Wilming L, Rand V, Lovering RC, Bruford EA, Khodiyar VK, Lush MJ, Povey S, Talbot CC Jr, Wright MW, Wain HM, Trowsdale J, Ziegler A, Beck S (2004)

Gene map of the extended human MHC.

Nat Rev Genet 5(12):889-899

This study characterises an integrated gene map of the extended human MHC, a pivotal region in the vertebrate genome for infection and autoimmunity due to its essential role in both adaptive and innate immunity, highlighting its significant content related to paralogy, polymorphism, immune functionality, and its association with various diseases, providing a comprehensive view stemming from the assimilation of data from several large-scale studies..

Jacob et al., 2002

Jacob S, McClitock MK, Zelano B and Ober C (2002)

Paternally inherited HLA alleles are associated with woman’s choice of male odour .

Nature Genetics, 30:175

This study demonstrates that women can discern differences in male body odor influenced by a single variance in HLA (human MHC) allele, with a woman's capacity to distinguish and prefer certain odors notably being based on HLA alleles inherited from her father and not her mother; this suggests that paternally inherited HLA-associated odors influence odor preference and might function as social cues, even despite a milieu of potential odors derived from a variety of genetic and cultural factors..

Milinski and Wedekind., 2001

Milinski M and Wedekind C (2001)

Evidence for MHC-correlated perfume preference in humans .

Behavioural Ecology 12(2):140-149

这项研究探讨了主要组织相容性复合体(MHC)基因型与人类香水偏好之间的关系。他们发现个体的MHC(具体来说是HLA-A、-B、-DR)与他们对各种个人使用香味的评分之间存在显著相关性,某些HLA类型(例如,HLA-A2)表现出一致的香味偏好。然而,在伴侣香味的偏好方面,这种相关性基本上不显著,这与假设一致,即个体选择个人使用的香水可能是为了增强或放大他们自身的免疫遗传体味,而不是为了改变伴侣的香味感知。

Wedekind et al., 1995

Wedekind C, Seebeck T, Bettens F And Paepke AJ (1995)

MHC-dependent mate preferences in humans.

Proc.R.Soc.Lond.B. 260:245-249.

这项研究发现,人们倾向于偏好那些免疫系统基因与自己不同的潜在伴侣的体味,但对于使用避孕药的女性来说,这种偏好会发生变化。

Jokiniemi et al., 2020

Jokiniemi A, Magris M, Ritari J, Kuusipalo L, Lundgren T, Partanen J and Kekäläinen J (2020)

交配后遗传配对:宫颈粘液对人类精子功能的HLA依赖性影响

Proc. R. Soc. B 287:20201682

* 发现精子活力与伴侣的HLA不相似性相关,这表明宫颈粘液可能选择性地促进免疫遗传相容伴侣之间的后期配子融合

Mosaad et al., 2011

Mosaad YM, Abdel-Dayem Y, El-Deek BS and El-Sherbini SM (2011)

埃及女性中HLA-E *0101纯合性与复发性流产之间的关联

Scand J Immunol. 2011 Aug;74(2):205-9. doi: 10.1111/j.1365-3083.2011.02559.x.

* found an increased frequency of homozygosity for HLA-E*0101 in Egyptian women with RM

Mora-Snchez 等人,2019

Mora-Sánchez A, Aguilar-Salvador D, Nowak I (2019)

朝着配子匹配平台:利用免疫遗传学和人工智能预测反复流产

NPJ Digit Med Mar 7;2:12.

* 提出了一个基因风险计算方法,可以通过分析有成功妊娠或反复流产(RM)历史的夫妇的HLA单倍型来预测反复流产。

Meuleman et al., 2015

Meuleman T, Lashley LE, Dekkers OM, van Lith J, Claas FH and Bloemenkamp KW (2015)

HLA 关联与反复流产中的 HLA 共享:一项系统评价和荟萃分析

Hum Immunol. May;76(5):362-73.

* 对41项研究进行了荟萃分析,显示HLA-B共享和HLA-DR共享均与RM的发生相关。

Shankarkumar et al., 2008

Shankarkumar U, Pawar A, Gaonkar P, Parasannavar D, Salvi V, and Ghosh K (2008)

来自印度的特发性复发性自然流产患者的HLA等位基因关联

J Hum Reprod Sci. 2008 Jan;1(1):19-24.

* 在与报告的世界RSA患者相比时,识别出HLA-A、HLA-B、HLA-C和HLA-DRB1等位基因的差异关联。

Ober, 1999

Ober C (1999)

对人类孤立种群中HLA、繁殖力和伴侣选择的研究

Hum Reprod Update 5(2):103-107.

* 描述HLA相似性在个体等位基因以及HLA单倍型之间的关系,作为Hutterite夫妇中胎儿流产风险增加的指标。

Ober et al., 1998

Ober C, Hyslop T, Elias S, Weitkamp LR, Hauck WW (1998)

人类白细胞抗原配型与胎儿丧失:一项为期10年的前瞻性研究结果

Human Reproduction, Volume 13, Issue 1, Jan 1998, Pages 33-38

* 一项为期10年的研究结果表明,HLA抗原匹配的Hutterite夫妇中胎儿流产率增加。

Ober et al., 1993

Ober., Steck., Ven., Billstrand., Messer., Kwak., Beaman., Beer (1993)

与反复自然流产夫妇的流产胎儿和足月婴儿的MHC II类兼容性

Journal of Reproductive Immunology, Volume 25, Issue 3, December 1993, Pages 195-207

* 在匹配 HLA-DQA1 等位基因的 Hutterite 夫妇中,显示出自发性流产复发率增加。

Lok., 2012

Lok C (2012)

Career development: What's your type ?

Nature, 488: 545-547

* 文章强调了迈尔斯-布里格斯性格类型指标及类似性格测试的应用,帮助科学家提升他们的软技能,并通过提供对其性格特征的洞察来引导他们的职业生涯,这些洞察可以为他们在专业环境中的沟通、领导和团队合作策略提供信息。

Keirsey., 2006

Keirsey, D (2006)

Please Understand Me II (3rd ed) .

Promethius Nemesis Book Co., Del Mar, CA.

《请你理解我》是大卫·凯尔西和玛丽莲·贝茨的心理学书籍,它采用自我评估问卷——凯尔西性格分类器,将个体分类为16种性格类型和4种更宽泛的性格类型(工匠、守护者、理性主义者和理想主义者),为读者提供对其行为模式和基本价值观的洞察,同时简化了以前的心理学理论和类型指标,尤其是米尔斯·布里格斯类型指标。

Moutafi et al., 2003

Myers et al., 1998

Myers IB, McCaulley MH, Quenk NL and Hammer AL (1998)

MBTI manual: A guide to the development and use of the Myers-Briggs Type Indicator .

Consulting Psychologists Press, Palo Alto, CA, Vol. 3.

MBTI®第三版手册是一本全面的指南,详细介绍了Myers-Briggs Type Indicator®仪器的发展、应用和解释,提供有关理论、可靠性和有效性的深入信息,并提供有关它识别的16种人格类型的见解,所有这些都是由心理类型领域的领先专家Isabel Briggs Myers、Mary H. McCaulley、Naomi L. Quenk和Allen L. Hammer撰写的。

Myers et al., 1985

Myers IB, McCaulley MH and Most R (1985)

手册,迈尔斯-布里格斯类型指标的开发和使用指南。

咨询心理学家出版社。

The 1985 edition, 'Manual: A Guide to the Development and Use of the Myers-Briggs Type Indicator,' introduces and elucidates the Myers-Briggs Type Indicator (MBTI®), designed to render C. G. Jung's psychological type theory comprehensible and applicable in daily life, underlining the principle that behavioral variations, while seemingly sporadic, are consistently orderly, deriving from intrinsic differences in individuals’ preferred use of perception and judgment.

Myers., 1962

Myers IB (1962)

手册,迈尔斯-布里格斯类型指标的开发和使用指南。

Consulting Psychologists Press .

The 1962 manual for the Myers-Briggs Type Indicator provides comprehensive insights and guidelines for implementing C. Jung’s theory of psychological types, asserting that behavioral variations are systematic and consistent due to basic perceptual and judgmental preferences, aiming to leverage these preferences through self-reports to ascertain individual psychological types, thereby enabling the practical application and research into their effects on reactions, motivations, values, and capabilities.

Jung., 1923

Jung CG (1923)

心理类型:或个体化心理学

Oxford, England: Harcourt, Brace .

Psychological Types by Carl Gustav Jung, first published in 1923, introduces the seminal psychological theory of psychological types, presenting a framework that seeks to explain the diverse and seemingly random differences in personality through a systematic and orderly theory, proposing that fundamental variations in human behavior arise due to inherent differences in how individuals prefer to utilize their cognitive functions of perception and judgment, laying the groundwork for numerous personality theories and assessments to come, notably the Myers-Briggs Type Indicator (MBTI).

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